Analysis of the interbeat interval increment to detect obstructive sleep apnoea/hypopnoea.
نویسندگان
چکیده
The prevalence of obstructive sleep apnoea/hypopnoea syndrome (OSAHS) is underestimated and its diagnosis is costly and restricted to specialised sleep laboratories. The frequency component of interbeat interval increment (III) has been proposed as a simple and inexpensive diagnostic tool in OSAHS. In a set of 150 patients with clinically suspected sleep-related breathing disorder, the actual predictive accuracy of the power spectral density of the III of the very low frequencies (%VLFI) was analysed by comparing with the apnoea/hypopnoea index (AHI), as assessed by synchronised polysomnography. OSAHS was defined in 100 patients according to an AHI>or=15 events.h(-1). Receiver operator characteristic curves built for %VLFI confirmed that this variable was able to separate OSAHS positive from OSAHS negative with statistical significance. Using an appropriate threshold (>4%), %VLFI demonstrated a positive predictive value of 80%. Misclassification of false-positive subjects occurred when the patient presented significant sleep discontinuity and sleep fragmentation (sleep fragmentation index>or=50 events.h(-1)) related to insomnia or periodic limb movements. A power spectral density of the interbeat interval increment of very low frequencies>4% allowed correct classification of obstructive sleep apnoea/hypopnoea syndrome when the clinical history suggested sleep-related breathing disorders and when moderate-to-severe cases are considered. Higher power spectral density of the interbeat interval increment of very low frequencies may also indicate disrupted sleep in the absence of clear clinical symptoms of sleep apnoea/hypopnoea syndrome.
منابع مشابه
Tumour necrosis factor-α/interleukin-10 ratio in patients with obstructive sleep apnoea hypopnoea syndrome.
OBJECTIVE To explore the significance of the tumour necrosis factor-α/interleukin-10 ratio and the effect of continuous positive airway pressure in patients with different degrees of obstructive sleep apnoea hypopnoea syndrome severity. METHOD This study comprised 135 patients with obstructive sleep apnoea hypopnoea syndrome and 94 control subjects. RESULTS Tumour necrosis factor-α and tumo...
متن کاملLonger term effects of very low energy diet on obstructive sleep apnoea in cohort derived from randomised controlled trial: prospective observational follow-up study
OBJECTIVE To determine whether initial improvements in obstructive sleep apnoea after a very low energy diet were maintained after one year in patients with moderate to severe obstructive sleep apnoea. DESIGN Single centre, prospective observational follow-up study. SETTING Outpatient obesity clinic in a university hospital in Stockholm, Sweden. PARTICIPANTS 63 men aged 30-65 with body ma...
متن کاملObstructive Sleep Apnoea Warning Signs of the Sleepy Snorer
Seven names 1 condition! The definition of sleep apnoea can be confusing because it is described in research literature under many guises: Obstructive Sleep apnoea (OSA) Sleep Apnoea (SA) Obstructive Sleep Apnoea Syndrome (OSAS) Sleep Apnoea/Hypopnoea Syndrome (SAHS) Obstructive Sleep Apnoea/Hypopnoea Syndrome (OSA/H) and of late, a new condition has been introduced Upper Airway Resistance Synd...
متن کاملHeart rate increment: an electrocardiological approach for the early detection of obstructive sleep apnoea/hypopnoea syndrome.
The prevalence of OSAHS (obstructive sleep apnoea/hypopnoea syndrome) is high in developed countries and it is estimated that the vast majority of patients remain undiagnosed. On the basis of physiological evidence, we evaluated the frequency component of HRI (heart rate increment) as a simple and inexpensive screening tool for OSAHS detection in a first group of patients (group 1) and validate...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- The European respiratory journal
دوره 29 6 شماره
صفحات -
تاریخ انتشار 2007